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Thus, in HUVECs, Mg 2+ deficiency promotes oxidative stress, and the upregulation of TXNIP seems to participate in the accumulation of ROS, triglycerides in lipid droplets, and hyperpermeability [202]
By inhibiting NNMT, it leads to an increase in intracellular levels of NAD+ (nicotinamide adenine dinucleotide), a critical coenzyme for cellular metabolism and mitochondrial energy production
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